Kodi Biofilms ndi chiyani?

M'mabulogu ndi makanema am'mbuyomu, takambirana zambiri za mabakiteriya a biofilms kapena plaque biofilms, koma ma biofilms ndi chiyani kwenikweni ndipo amapanga bwanji?

Kwenikweni, ma biofilms ndi unyinji waukulu wa mabakiteriya ndi bowa omwe amamatira pamwamba kudzera pa chinthu chonga guluu chomwe chimakhala ngati nangula komanso chitetezero ku chilengedwe.Izi zimathandiza kuti mabakiteriya ndi bowa zomwe zili mkati mwake zikule mozungulira komanso molunjika.Tizilombo tating'onoting'ono tomwe timalumikizana ndi zomatazi timakhalanso mufilimuyi tikupanga ma biofilms amitundu yambiri ya mabakiteriya ndi bowa omwe amaphatikizana kukhala mazana ndi mazana a zigawo zokhuthala.Matrix onga guluu amapangitsa kuchiza ma biofilmswa kukhala kovuta kwambiri chifukwa maantimicrobials ndi chitetezo chamthupi sichingathe kulowa mkati mwa makanemawa zomwe zimapangitsa kuti zamoyozi zisamve chithandizo chamankhwala ambiri.

Mafilimu a biofilm ndi othandiza kwambiri kotero kuti amalimbikitsa kulolerana kwa maantibayotiki mwa kuteteza thupi majeremusi.Amatha kupanga mabakiteriya mpaka nthawi 1,000 kugonjetsedwa ndi maantibayotiki, mankhwala ophera tizilombo komanso chitetezo cham'thupi ndipo asayansi ambiri amadziwika kuti ndi chimodzi mwazomwe zimayambitsa kukana kwa ma antibiotic padziko lonse lapansi.

Ma biofilms amatha kupanga pazinthu zamoyo komanso zopanda moyo kuphatikiza mano (zolemba ndi tartar), khungu (monga mabala ndi seborrheic dermatitis), makutu (otitis), zida zamankhwala (monga ma catheters ndi endoscopes), masinki akukhitchini ndi ma countertops, chakudya ndi chakudya. zida zopangira, malo azipatala, mapaipi ndi zosefera m'mafakitale opangira madzi ndi mafuta, gasi ndi petrochemical process control station.

Kodi ma biofilms amapangidwa bwanji?

Tizilombo toyambitsa matenda ndi mafangasi timakhala tikupezeka mkamwa ndipo nthawi zonse amayesa kuyika mano pakamwa pogwira molimba ngati guluu.(Nyenyezi zofiira ndi zabuluu m’fanizoli zikuimira mabakiteriya ndi mafangayi.)

Mabakiteriya ndi mafangawa amafunikira chakudya kuti athandizire kukula ndi kukhazikika kwa membrane.Izi makamaka zimachokera ku ayoni achitsulo omwe amapezeka mwachilengedwe mkamwa monga chitsulo, calcium ndi magnesium, pakati pazinthu zina.(Madontho obiriwira m’fanizoli akuimira ayoni achitsulowa.)

Mabakiteriya ena amasonkhana pamalowa kuti apange timagulu ting'onoting'ono, ndipo amapitirizabe kutulutsa chinthu chomatachi ngati chotchinga ngati dome chomwe chimatha kuteteza chitetezo cha mthupi, antimicrobials ndi mankhwala ophera tizilombo.(Nyenyezi zofiirira zomwe zili m’fanizoli zikuimira mitundu ina ya mabakiteriya ndipo chobiriwiracho chimaimira kuchulukana kwa matrix a biofilm.)

Pansi pa biofilm yomata iyi, mabakiteriya ndi mafangasi amachulukana mwachangu kupanga gulu la 3-dimensional, lamitundu yambiri lomwe limadziwikanso kuti dental plaque lomwe kwenikweni ndi biofilm yokhuthala mazana ndi mazana a zigawo zakuya.Biofilm ikafika pachimake, imatulutsa mabakiteriya ena kuti ayambitsenso kufalikira kwa malo ena olimba a mano ndikupangitsa kuti plaque pamalo onse a mano apangidwe.(Zobiriwira m'chifanizochi zikuwonetsa biofilm ikukula ndikukulitsa dzino.)

M'kupita kwa nthawi, ma plaque biofilms, kuphatikiza ndi mchere wina m'kamwa, amayamba kuwerengeka, ndikusandulika kukhala chinthu cholimba kwambiri, cholimba, chokhala ngati fupa chotchedwa calculus, kapena tartar.(Izi zikuimiridwa mu fanizo ndi nyumba yachikaso ya filimu yachikasu yomwe ili m'mphepete mwa chingamu pansi pa mano.)

Tizilombo toyambitsa matenda timapitirizabe kupanga zomangira ndi tartar zomwe zimalowa pansi pa chingamu.Izi, kuphatikiza ndi zida zakuthwa, zokhotakhota zimakwiyitsa ndi kukanda mkamwa pansi pa chingamu zomwe zimatha kuyambitsa periodontitis.Ngati sichitsatiridwa, imatha kuyambitsa matenda amtundu uliwonse omwe amakhudza mtima wa chiweto chanu, chiwindi ndi impso.(Mtundu wa filimu wachikasu m’chifanizochi ukuimira mbali zonse za filimuyo zomwe zimawerengeredwa ndikukula pansi pa chingamu.)

Malinga ndi kuyerekezera kwa National Institute of Health (NIH, USA), pafupifupi 80% ya matenda onse oyambitsidwa ndi mabakiteriya a anthu amayamba ndi biofilms.

Kane Biotech imagwira ntchito yopititsa patsogolo ukadaulo ndi zinthu zomwe zimaphwanya ma biofilm ndikuwononga mabakiteriya.Kuwonongeka kwa biofilms kumapangitsa kuchepetsa kwambiri kugwiritsa ntchito mankhwala oletsa tizilombo toyambitsa matenda ndipo motero kutenga nawo mbali mwanzeru komanso mogwira mtima kugwiritsa ntchito mankhwalawa.

Ukadaulo wopangidwa ndi Kane Biotech wa bluestem ndi silkstem uli ndi zotsatira zabwino pa thanzi la anthu, nyama komanso chilengedwe.